Schizophrenia

On November 27, 2014, the Division of Clinical Psychology of the British Psychological Society published a paper titled Understanding Psychosis and Schizophrenia. The paper was edited by Anne Cooke of Canterbury Christ Church University. The central theme of the paper is that the condition known as psychosis is better understood as a response to adverse life events rather than as a symptom of neurological pathology. The paper was wide ranging and insightful, and, predictably, drew support from most of us on this side of the issue and criticism from psychiatry. Section 12 of the paper is headed “Medication” and under the subheading “Key Points”, you’ll find this quote: ...

There’s an interesting article in the June 2014 issue of the Journal of ECT. It’s written by Max Fink, MD, and is titled Celebrating 80 Years of Inducing Brain Seizures as Psychiatric Treatment. Dr. Fink is a psychiatrist and neurologist, and professor emeritus of psychiatry and neurology at the State University of New York, Stony Brook. The article is short (approximately 400 words), and is essentially a tribute to Ladislas Meduna for his discovery “…that induced seizures alleviated severe psychiatric disorders…”, which Dr. Fink describes as “…a remarkable medical advance…” ...

In November 2013, the journal Schizophrenia Research published a paper by Tsuji, T. et al. titled Premorbid teacher-rated social functioning predicts adult schizophrenia-spectrum disorder: A high-risk prospective investigation. Here’s the abstract: "Social functioning deficits are a core component of schizophrenia spectrum disorders, and may emerge years prior to the onset of diagnosable illness. The current study prospectively examines the relation between teacher-rated childhood social dysfunction and later mental illness among participants who were at genetic high-risk for schizophrenia and controls (n=244). The teacher-rated social functioning scale significantly predicted psychiatric outcomes (schizophrenia-spectrum vs. other psychiatric disorder vs. no mental illness). Poor premorbid social functioning appears to constitute a marker of illness vulnerability and may also function as a chronic stressor potentially exacerbating risk for illness." ...

In January 2014, the journal Research on Social Work Practice ran a special issue called A Critical Appraisal of the DSM-5: Social Work Perspectives. There are fifteen articles on this general theme, and together they present a wide range of arguments against the DSM system. Social workers represent the numerically biggest group of mental health practitioners in the US, and it is particularly gratifying to see a major social work journal addressing this topic so forthrightly. ...

INTRODUCTION An NBC online News article dated October 15, 2010, carried the noteworthy title New blood test may help detect schizophrenia. Thanks to Francesca for the link. The article was written by Natasha Allen, a freelance medical journalist. The gist of the article is that there is a new blood test called VeriPsych which “researchers say” is 83% accurate in discriminating people who are “schizophrenic” from people who are not. ...

On November 12, 2013, Molecular Psychiatry published online Evidence that duplications of 22q11.2 protect against schizophrenia, by Rees et al. The print version was published last month – January 2014. Here’s the authors’ summary: "A number of large, rare copy number variants (CNVs) are deleterious for neurodevelopmental disorders, but large, rare, protective CNVs have not been reported for such phenotypes. Here we show in a CNV analysis of 47 005 individuals, the largest CNV analysis of schizophrenia to date, that large duplications (1.5–3.0 Mb) at 22q11.2—the reciprocal of the well-known, risk-inducing deletion of this locus—are substantially less common in schizophrenia cases than in the general population (0.014% vs. 0.085%, OR=0.17, P=0.00086). 22q11.2 duplications represent the first putative protective mutation for schizophrenia." ...

Psychiatric News is the APA’s online bulletin. On Jan 15, it ran an article by Vabren Watts (an APA staff writer). The article is called APA Gives Schizophrenia Research Capitol Hill Spotlight. It is reported in the article that on December 12, 2013, the APA, together with the Congressional Neuroscience Caucus and the American Brain Coalition, made a joint presentation to legislators and their staffs on ...

BACKGROUND There has been some discussion in recent weeks concerning the role of childhood abuse in the etiology of the condition known as schizophrenia. It is particularly difficult to address this problem because the condition known as schizophrenia is not a unified phenomenon. Rather, it is an assortment of loosely clustered behaviors which has been falsely and illogically labeled by the APA as an illness, existing in an individual. So the question “Is schizophrenia caused by childhood abuse?” is a meaningless question. In other words, it cannot be answered either as “true” or “false.” In fact, it can’t even be answered “maybe.” ...

There’s an interesting article on Vermont’s Seven Days. It’s called Burlington’s HowardCenter Tries a New Approach to Treating Mental Illness: More Talk, Fewer Meds. You can see it here. (Thanks to Steven Coles on Twitter for the link.) Apparently Vermont’s Department of Mental Health is promoting a “new” kind of treatment for psychosis: talk therapy. The project leader is Dr. Sandra Steingard, who for most of her career accepted the orthodox view of schizophrenia and the need for neuroleptic drugs. ...

There’s an important article (here) on Monica Cassani’s website BeyondMeds in which she tackles the myth that once a person has been assigned a “diagnosis” of schizophrenia, he/she must take neuroleptics for life. Here’s a quote: "Unfortunately, at this juncture in history many people who get labeled with psychiatric illness these days do not have the opportunity for recovery because they are encouraged to stay ill by a system that all too often impedes psychological growth by use of excessive psychotropic drugs. This over-use of medication also kills people. The average life-span of people taking these medications is 25 years shorter than people who do not take these drugs. The drugs cause a long laundry list of problems only some of which are diabetes, obesity, heart conditions and a shrinking brain." ...